| 1. | André-Pierre Gignac
Tigres UANL | France | 30 | 24 |
| 2. | Mauro Boselli
Leon | Argentina | 31 | 22 |
| 3. | Dayro Moreno
Tijuana | Colombia | 30 | 19 |
| 4. | Rogelio Funes Mori
Monterrey | Argentina | 25 | 18 |
| | Silvio Romero
Chiapas FC | Argentina | 27 | 18 |
| 6. | Edwin Cardona
Monterrey | Colombia | 23 | 16 |
| | Emanuel Villa
Querétaro | Argentina | 34 | 16 |
| | Enrique Triverio
Toluca | Argentina | 27 | 16 |
| 9. | Carlos Pena
Leon | Mexico | 26 | 15 |
| | Oribe Peralta
América | Mexico | 32 | 15 |
| 11. | Dorlan Pabon
Monterrey | Colombia | 28 | 14 |
| | Franco Jara
Pachuca | Argentina | 27 | 14 |
| | Ismael Sosa
Pumas UNAM | Argentina | 29 | 14 |
| 14. | Eduardo Herrera
Pumas UNAM | Mexico | 27 | 13 |
| 15. | Omar Bravo
Guadalajara | Mexico | 36 | 12 |
| 16. | Jorge Benitez
Cruz Azul | Paraguay | 23 | 11 |
| | Julio Furch
C.D. Veracruz | Argentina | 26 | 11 |
| 18. | Darwin Quintero
América | Colombia | 28 | 10 |
| | Djaniny
Santos Laguna | Cape Verde | 25 | 10 |
| | Fernando Uribe
Toluca | Colombia | 28 | 10 |
| | Hirving Lozano
Pachuca | Mexico | 20 | 10 |
| | Juan Pablo Rodriguez
Monarcas Morelia | Mexico | 36 | 10 |
| | Luis Gabriel Rey
Puebla F.C. | Colombia | 36 | 10 |
| | Matías Alustiza
Puebla F.C. | Argentina | 31 | 10 |
| | Matias Britos
Pumas UNAM | Uruguay | 27 | 10 |
| | Pablo Velázquez
Monarcas Morelia | Paraguay | 29 | 10 |
