| 1. | Lionel Messi
Barcelona | Argentina | 22 | 8 |
| 2. | Cristiano Ronaldo
Real Madrid | Portugal | 25 | 7 |
| | Ivica Olic
Bayern München | Croatia | 30 | 7 |
| 4. | Diego Milito
Inter | Argentina | 30 | 6 |
| 5. | Marouane Chamakh
Bordeaux | Morocco | 26 | 5 |
| | Nicklas Bendtner
Arsenal | Denmark | 22 | 5 |
| | Wayne Rooney
Manchester United | England | 24 | 5 |
| 8. | Arjen Robben
Bayern München | Netherlands | 26 | 4 |
| | Cesc Fabregas
Arsenal | Spain | 23 | 4 |
| | Edin Dzeko
Wolfsburg | Bosnia and Herzegovina | 24 | 4 |
| | Radamel Falcao
Porto | Colombia | 24 | 4 |
| | Michael Owen
Manchester United | England | 30 | 4 |
| | Milos Krasic
CSKA Moscow | Serbia | 25 | 4 |
| | Miralem Pjanic
Lyon | Bosnia and Herzegovina | 20 | 4 |
| | Pedro Rodriguez
Barcelona | Spain | 22 | 4 |
| | Stevan Jovetic
Fiorentina | Montenegro | 20 | 4 |
| | Zlatan Ibrahimovic
Barcelona | Sweden | 28 | 4 |
| 18. | Adrian Mutu
Fiorentina | Romania | 31 | 3 |
| | Alan Dzagoev
CSKA Moscow | Russia | 19 | 3 |
| | Alberto Gilardino
Fiorentina | Italy | 27 | 3 |
| | Didier Drogba
Chelsea | Ivory Coast | 32 | 3 |
| | Grafite
Wolfsburg | Brazil | 31 | 3 |
| | Hulk
Porto | Brazil | 23 | 3 |
| | Lisandro López
Lyon | Argentina | 27 | 3 |
| | Michaël Ciani
Bordeaux | France | 26 | 3 |
| | Nicolas Anelka
Chelsea | France | 31 | 3 |
| | Paul Scholes
Manchester United | England | 35 | 3 |
| | Ronaldinho
Milan | Brazil | 30 | 3 |
| | Salomon Kalou
Chelsea | Ivory Coast | 24 | 3 |
| | Samir Nasri
Arsenal | France | 22 | 3 |
| | Wesley Sneijder
Inter | Netherlands | 25 | 3 |
