| 1. | Dmitri Kirichenko
FC Moscow | Russia | 28 | 14 |
| 2. | Derlei
Dynamo Moscow | Brazil | 30 | 13 |
| 3. | Igor Semshov
Torpedo Moscow | Serbia | 27 | 12 |
| 4. | Roman Pavlyuchenko
Spartak Moscow | Russia | 23 | 11 |
| 5. | Aleksandr Panov
Torpedo Moscow | Russia | 30 | 10 |
| | Ivica Olic
CSKA Moscow | Croatia | 26 | 10 |
| 7. | Andrey Arshavin
Zenit St.Petersburg | Russia | 24 | 9 |
| | Dzhambulad Bazayev
Alania Vladikavkaz | Russia | 26 | 9 |
| 9. | Diniyar Bilyaletdinov
Lokomotiv Moscow | Russia | 20 | 8 |
| | Maksim Buznikin
Lokomotiv Moscow/Rostov | Russia | 28 | 8 |
| 11. | Aleksandr Kerzhakov
Zenit St.Petersburg | Russia | 22 | 7 |
| | Andriy Husin
Krylia Sovetov | Ukraine | 32 | 7 |
| | Roman Adamov
Akhmat Groznyi | Russia | 23 | 7 |
| | Tomás Cizek
Rubin Kazan | Czech Republic | 26 | 7 |
| | Vágner Love
CSKA Moscow | Brazil | 21 | 7 |
| 16. | Alejandro Dominguez
Rubin Kazan | Argentina | 24 | 6 |
| | Dmitri Loskov
Lokomotiv Moscow | Russia | 31 | 6 |
| | Dmitri Sychev
Lokomotiv Moscow | Russia | 22 | 6 |
| | Fernando Cavenaghi
Spartak Moscow | Argentina | 22 | 6 |
| | Igor Lebedenko
Lokomotiv Moscow | Russia | 22 | 6 |
| | Oleksandr Spivak
Zenit St.Petersburg | Ukraine | 30 | 6 |
| | Sergiu Dadu
Alania Vladikavkaz | Moldova | 24 | 6 |
| | Spartak Gogniyev
Alania Vladikavkaz | Russia | 24 | 6 |
| | Wladimir Baýramow
Rubin Kazan | Turkmenistan | 25 | 6 |
